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Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
Published on: February 7, 2019
3,9-Dimethyl-2,3-dihydro-spiro-[carb-az-ole-1,2'-[1,3]dithio-lan]-4(9H)-one
Sibel Gülle1, Nagihan Caylak Delibaş, Yavuz Ergün
1Celal Bayar University, Faculty of Arts and Sciences, Department of Chemistry, 45030 Muradiye, Manisa, Turkey.
Abstract:
The title compound, C16H17NOS2, consists of a carbazole skeleton with methyl and dithiol-ane groups as substituents. In the indole ring system, the benzene and pyrrole rings are nearly coplanar, forming a dihedral angle of 1.02 (11)°. The cyclo-hexenone ring has a twisted conformation, while the dithiol-ane ring adopts an envelope conformation with one of the CH2 C atoms at the flap. In the crystal, weak C-H⋯O hydrogen bonds link the mol-ecules into supra-molecular chains nearly parallel to the c axis. These hydrogen bonds together with weak C-H⋯π inter-actions link the molecules into a three-dimensional supramolecular network.
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