Related Experiment Video
Updated: May 11, 2026

Induction of Paralysis and Visual System Injury in Mice by T Cells Specific for Neuromyelitis Optica Autoantigen Aquaporin-4
Published on: August 21, 2017
[Neuromyelitis optica is a frequently seen inflammatory demyelinating disease]
Nasrin Asgari1, Hanne Pernille Bro Skejø, Søren Thue Lillevang
1Neurologisk Afdeling, Sygehus Lillebælt Vejle, Vejle Sygehus, Kabbeltoft 25, 7100 Vejle, Denmark. nasgari@health.sdu.dk
Abstract:
Neuromyelitis optica (NMO) is an inflammatory demyelinating disease of the central nervous system with autoimmune characteristics. Serum immunoglobulin G autoantibodies have been identified in the majority of NMO patients with the water channel aquaporin-4 (AQP4) as their main target autoantigen. Clinical criteria have defined NMO and NMO-spectrum disease. The clinical features include inflammation of the optic nerve.
Related Concept Videos
Multiple Sclerosis l: Introduction
Encephalitis ll: Pathophysiology
Encephalitis l: Introduction
