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The WU-Minn Human Connectome Project: an overview
David C Van Essen1, Stephen M Smith, Deanna M Barch
1Department of Anatomy & Neurobiology, Washington University School of Medicine, 660 S. Euclid Avenue, St. Louis, MO 63110, USA. vanessen@wustl.edu
The Human Connectome Project (HCP) is mapping brain circuits and behavior in adults. Early results show high-quality data and accessible datasets, promising valuable resources for neuroscience research.
Area of Science:
- Neuroscience
- Human Brain Mapping
- Connectomics
Background:
- The Human Connectome Project (HCP) consortium aims to map human brain circuits.
- Understanding the relationship between brain structure, function, and behavior is a key goal.
- A large population of healthy adults is being studied.
Purpose of the Study:
- To report progress in the first half of the 5-year HCP.
- To detail advancements in data acquisition and analysis methods.
- To highlight the accessibility of HCP data.
Main Methods:
- Systematic mapping of macroscopic human brain circuits.
- Utilizing advanced neuroimaging and behavioral data acquisition techniques.
- Developing and refining data analysis protocols.
Main Results:
- Preliminary analyses confirm exceptionally high data quality across modalities.
- The first quarterly release of imaging and behavioral data is available via ConnectomeDB.
- Protocols for data acquisition and preprocessing have been finalized.
Conclusions:
- The HCP is on track to provide valuable resources for brain connectivity research.
- HCP datasets, methods, and software will advance the study of brain function and behavior.
- Future research will benefit from understanding the heritability and genetic underpinnings of brain connectivity.
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