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Updated: May 11, 2026

12:22
Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy (oSLO) and Optical Coherence Tomography (OCT)
Published on: August 4, 2018
[Placido topography combined with optical biometry--first results]
T Oltrup1, M A Leitritz, B Voykov
1Stiftungslabor für Grundlagenforschung, Universitäts-Augenklinik Tübingen, Schleichstrasse 12, Tübingen. toltrup@deos-tuebingen.de
Summary
A new optical biometry system (BioTop) shows accurate axial length measurements comparable to the IOLMaster, enabling customized intraocular lens (IOL) calculations.
Area of Science:
- Ophthalmology
- Biomedical Engineering
- Optical Metrology
Context:
- Optical biometry is crucial for intraocular lens (IOL) power calculation.
- Zeiss IOLMaster is a widely used device for optical biometry.
- A novel system, BioTop, integrates video topography with optical coherence biometry.
Purpose:
- To evaluate the axial length measurement accuracy of the new BioTop system.
- To compare the BioTop system's performance against the established Zeiss IOLMaster (versions 3 and 5).
- To assess the clinical relevance of measurement differences in cataractous eyes.
Summary:
- The BioTop system demonstrated high accuracy in measuring a known reference length (20.011 ± 0.001 mm).
- Comparisons with IOLMaster versions 3 and 5 showed mean axial length differences of -0.015 mm in cataract eyes.
- Both systems exhibited high accuracy on the reference, with minor, clinically irrelevant differences observed between them in cataract patients.
Impact:
- The BioTop system provides accurate axial length measurements for IOL calculations.
- The integration of topography and biometry offers advanced capabilities for customized IOL design using ray-tracing.
- This technology expands options for precise intraocular lens calculations and personalized vision correction.
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