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Updated: May 11, 2026
07:27
Recurrent Herpetic Stromal Keratitis in Mice, a Model for Studying Human HSK
Published on: December 18, 2012
Recurrent bacterial keratitis
Rebecca Kaye1, Abigail Kaye, Henri Sueke
1St. Paul's Eye Unit, Royal Liverpool University Hospital, Liverpool, United Kingdom. s.b.kaye@liverpool.ac.uk
Investigative Ophthalmology & Visual Science
|May 23, 2013
Summary
Recurrent bacterial keratitis is often linked to Staphylococcus aureus. Addressing S. aureus colonization may prevent repeat infections and reduce the need for corneal transplants.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Microbiology
Background:
- Bacterial keratitis is an eye infection that can lead to vision loss.
- Recurrent cases pose significant challenges in treatment and management.
- Understanding causative agents and risk factors for recurrence is crucial.
Purpose of the Study:
- To determine the incidence of recurrent bacterial keratitis.
- To identify bacteria associated with recurrent infections.
- To analyze the need for surgical intervention in recurrent cases.
Main Methods:
- Retrospective analysis of bacterial keratitis cases from 1995-2010.
- Identification of bacterial isolates from microbiological requests.
- Correlation of recurrence, bacterial type, and surgical procedures.
Main Results:
- Over 12% of patients experienced recurrent bacterial keratitis.
- Staphylococcus aureus isolation increased with higher recurrence rates.
- S. aureus-associated keratitis led to a higher rate of corneal transplantation.
Conclusions:
- Staphylococcus aureus is a key pathogen in recurrent bacterial keratitis.
- Identifying and treating infection sources is vital for preventing recurrence.
- S. aureus decolonization may be a viable strategy for patients with recurrent keratitis.
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