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A High-throughput Platform for the Screening of Salmonella spp./Shigella spp.
Published on: November 7, 2018
Quantifying the incidence and burden of postinfectious enteric sequelae
Chad K Porter1, Nadia Thura, Mark S Riddle
1Enteric Diseases Department, Infectious Disease Research Directorate, Naval Medical Research Center, 503 Robert Grant Avenue, Silver Spring, MD 20910-7500, USA.
Military Medicine
|May 28, 2013
Summary
Travelers' diarrhea (TD) can lead to chronic health issues, with significant disability burdens comparable to post-traumatic stress disorder (PTSD). Improving prevention strategies for TD is crucial for troop readiness and long-term health.
Area of Science:
- Global health
- Military medicine
- Epidemiology
Background:
- Travelers' diarrhea (TD) is increasingly linked to chronic health conditions.
- The long-term health outcomes (LTHO) of TD sequelae (TDS) require further quantification.
- Comparison of TDS burden with well-studied deployment outcomes like post-traumatic stress disorder (PTSD) and mild traumatic brain injury (mTBI) is needed.
Purpose of the Study:
- To quantify the disease burden of TD sequelae (TDS).
- To compare the disability burden of TDS with PTSD and mild traumatic brain injury (mTBI).
Main Methods:
- A systematic review was conducted.
- Outcome-specific incidence and disability data were analyzed.
- Years lived with disability (YLDs) were estimated for comparative analysis.
Main Results:
- Disability estimates varied based on study design and data source.
- Post-traumatic stress disorder (PTSD) showed the highest overall disability (1,225 per 100,000).
- TD sequelae (TDS) demonstrated significant burdens, particularly irritable bowel syndrome (627 per 100,000) and reactive arthritis (139 per 100,000).
Conclusions:
- The long-term health outcomes (LTHO) of TD are substantial and impact troop readiness.
- Enhanced primary prevention strategies for TD are essential.
- Further research into pathogen-specific risks and disability duration is needed to inform policy.
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