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Related Concept Videos

Staphylococcal Skin Infections01:29

Staphylococcal Skin Infections

Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
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Clinical Significance of Antibiotic Resistance

Methicillin-resistant Staphylococcus aureus (MRSA) presents a critical public health threat, arising from its capacity to resist β-lactam antibiotics due to acquisition of the mecA gene within the staphylococcal cassette chromosome mec (SCCmec). This gene encodes penicillin-binding protein 2a (PBP2a), which impairs binding efficacy of methicillin and other β-lactams. MRSA has evolved into distinct clonal lineages impacting humans and animals alike, reinforcing its significance within the One...
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Bacterial Meningitis II: Pathophysiology

Bacterial meningitis typically begins when pathogens such as Neisseria meningitidis and Streptococcus pneumoniae colonize the nasopharynx and invade the bloodstream. This process is facilitated by bacterial virulence factors, such as polysaccharide capsules, which resist phagocytosis and complement-mediated killing. Less commonly, bacteria reach the central nervous system via contiguous spread from infections like otitis media or sinusitis, through congenital or acquired dural defects, or...
Bacterial Meningitis I: Introduction01:22

Bacterial Meningitis I: Introduction

Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...
Brain Abscess l: Introduction01:26

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Related Experiment Video

Updated: May 11, 2026

Intracranial Subarachnoidal Route of Infection for Investigating Roles of Streptococcus suis Biofilms in Meningitis in a Mouse Infection Model
07:26

Intracranial Subarachnoidal Route of Infection for Investigating Roles of Streptococcus suis Biofilms in Meningitis in a Mouse Infection Model

Published on: July 1, 2018

[Septic arthritis caused by Streptococcus suis].

Sofie Sommer Hedegaard1, Matthias Zaccarin, Jens Lindberg

  • 1Medicinsk Afdeling, Regionshospitalet Herning, Gl. Landevej 61, 7400 Herning, Denmark. sosom@dadlnet.dk

Ugeskrift for Laeger
|June 1, 2013
PubMed
Summary

Streptococcus suis, a swine pathogen, can infect humans causing serious conditions like meningitis. Early diagnosis and proper treatment are vital for favorable outcomes in rare disseminated arthritis cases.

Related Experiment Videos

Last Updated: May 11, 2026

Intracranial Subarachnoidal Route of Infection for Investigating Roles of Streptococcus suis Biofilms in Meningitis in a Mouse Infection Model
07:26

Intracranial Subarachnoidal Route of Infection for Investigating Roles of Streptococcus suis Biofilms in Meningitis in a Mouse Infection Model

Published on: July 1, 2018

Area of Science:

  • Veterinary Medicine
  • Infectious Diseases
  • Microbiology

Background:

  • Streptococcus suis is a significant swine pathogen with zoonotic potential.
  • Human infections, though sporadic, can lead to severe conditions such as meningitis, endocarditis, and sepsis.
  • An outbreak in China documented 215 human cases.

Observation:

  • A rare case of disseminated arthritis caused by S. suis presented diagnostic challenges.
  • Unspecific symptoms and slow bacterial growth complicated early and accurate clinical diagnosis.

Findings:

  • Despite diagnostic difficulties, thorough examinations are crucial for identifying S. suis infections.
  • Prompt and appropriate treatment leads to favorable patient outcomes.

Implications:

  • Highlights the importance of considering S. suis in human infections, especially with swine exposure.
  • Emphasizes the need for advanced diagnostic approaches for challenging presentations of S. suis.
  • Underscores the treatability of S. suis infections when managed effectively.