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Minimally invasive aortic valve replacement with self-anchoring Perceval valve
Malakh Shrestha1, Rebecca Timm, Klaus Höffler
1Division of Cardio-thoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany. Shrestha.Malakh.Lal@mh-hannover.de
The Journal of Heart Valve Disease
|June 27, 2013
Summary
The self-anchoring Perceval S valve offers a reproducible option for minimally invasive aortic valve replacement (AVR). This technique reduces procedure times and may expand the use of minimally invasive AVR.
Area of Science:
- Cardiovascular Surgery
- Medical Devices
- Minimally Invasive Procedures
Background:
- Minimally invasive aortic valve replacement (AVR) shows promise for reduced patient morbidity but lacks widespread adoption.
- The Perceval S self-anchoring valve is a novel device designed for less invasive procedures.
Purpose of the Study:
- To evaluate the feasibility and outcomes of implanting the Perceval S self-anchoring aortic valve through a mini-sternotomy approach.
- To assess the safety and efficacy of this technique in patients with isolated aortic valve stenosis.
Main Methods:
- A prospective, non-randomized clinical trial involving 35 patients undergoing AVR with the Perceval S valve via mini-sternotomy.
- Standard extracorporeal circulation (ECC) and aortic cross-clamping were employed.
- Patient demographics and procedural data, including EuroSCORE and STS scores, were recorded.
Main Results:
- No deployment failures, intra-procedure, or 30-day mortality were observed.
- Mean ECC time was 70 minutes, and cross-clamp time was 34 minutes, with valve implantation averaging 9 minutes.
- Postoperative echocardiography showed no significant paravalvular leakage or aortic insufficiency; no prosthesis migration occurred.
Conclusions:
- The Perceval S valve provides a technically reproducible solution for minimally invasive AVR.
- Its self-anchoring mechanism negates the need for suturing, simplifying implantation even in challenging aortic root anatomies.
- This approach has the potential to reduce procedure times and facilitate broader adoption of minimally invasive AVR.
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