Handgrip strength in autism spectrum disorder compared with controls.

Area of Science:

• Neurology
• Developmental Pediatrics
• Musculoskeletal Health

Background:

• Autism spectrum disorder (ASD) is a neurodevelopmental condition affecting social interaction and communication.
• Limited research exists on the physical characteristics, specifically muscle strength, in children with ASD.
• Handgrip strength is a reliable indicator of overall muscle strength and functional capacity.

Purpose of the Study:

• To compare handgrip strength between children diagnosed with ASD and age-matched neurotypical controls.
• To investigate potential muscle weakness as a physical characteristic associated with ASD.
• To explore the utility of handgrip strength measurement in assessing interventions for ASD.

Main Methods:

• A comparative study involving 33 children with ASD and 33 neurotypical controls, aged 2-17 years.
• Participants were matched for gender, race, and age.
• Handgrip strength was measured using a handheld dynamometer.

Main Results:

• Children with ASD exhibited significantly lower handgrip strength than neurotypical controls (p < 0.0001).
• Mean handgrip strength was 39.4 ± 17.7 kPa for children with ASD versus 65.1 ± 26.7 kPa for controls.
• The findings support the hypothesis of reduced handgrip strength in children with ASD.

Conclusions:

• Children with ASD demonstrate significantly weaker handgrip strength compared to their neurotypical peers.
• The results suggest underlying muscle weakness in the ASD population.
• Handgrip strength assessment may serve as a valuable tool for evaluating targeted treatments and understanding physical development in ASD.