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Updated: May 8, 2026

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3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
Published on: June 2, 2014
Approach to acute headache in adults.
Barry L Hainer1, Eric M Matheson
1Medical University of South Carolina, Charleston, SC, USA. hainerbl@musc. edu
American Family Physician
|August 14, 2013
Summary
Headache disorders affect half the world's adults. Recognizing primary headache features and red flags helps doctors diagnose causes, reducing unnecessary tests like neuroimaging.
Area of Science:
- Neurology
- Internal Medicine
Background:
- Headache disorders are highly prevalent, affecting approximately 50% of the global adult population.
- Accurate diagnosis is crucial for effective management and patient care.
Purpose of the Study:
- To outline diagnostic criteria for differentiating primary and secondary headaches.
- To identify key clinical features and "red flag" symptoms that necessitate further investigation.
Main Methods:
- Utilizing the International Headache Society classification and diagnostic criteria.
- Emphasizing thorough patient history and physical examination.
- Reviewing indications for neuroimaging and other diagnostic studies.
Main Results:
- A detailed history and physical exam can often differentiate primary headaches (e.g., migraine, tension-type, cluster) from secondary causes.
- Specific "red flag" symptoms (e.g., sudden onset, focal neurologic signs, papilledema, neck stiffness) indicate potential serious underlying pathology.
- Head computed tomography without contrast is recommended for suspected intracranial hemorrhage; MRI or CT are acceptable for other dangerous causes.
Conclusions:
- Physicians can effectively diagnose headache disorders by understanding primary headache features and recognizing red flags.
- Appropriate use of diagnostic criteria and clinical assessment can minimize the need for extensive, costly investigations.
- Prompt identification of red flag symptoms ensures timely evaluation for serious conditions causing headaches.
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