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Updated: May 8, 2026
Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla
Published on: February 19, 2021
7 Tesla MRI with a transmit/receive loopless antenna and B1-insensitive selective excitation
M Arcan Erturk1, AbdEl-Monem M El-Sharkawy, Jay Moore
1Department of Electrical and Computer Engineering, Johns Hopkins University, Baltimore, Maryland, USA; Russell H. Morgan Department of Radiology and Radiological Sciences, Johns Hopkins University, Baltimore, Maryland, USA.
Purpose:
Use of external coils with internal detectors or conductors is challenging at 7 Tesla (T) due to radiofrequency (RF) field (B1 ) penetration, B1 -inhomogeneity, mutual coupling, and potential local RF heating. The present study tests whether the near-quadratic gains in signal-to-noise ratio and field-of-view with field-strength previously reported for internal loopless antennae at 7T can suffice to perform MRI with an interventional transmit/receive antenna without using any external coils.
Methods:
External coils were replaced by semi-rigid or biocompatible transmit/receive loopless antennae requiring only a few Watts of peak RF power. Slice selection was provided by spatially selective B1 -insensitive composite RF pulses that compensate for the antenna's intrinsically nonuniform B1 -field. Power was adjusted to maintain local temperature rise ≤1°C. Fruit, intravascular MRI of diseased human vessels in vitro, and MRI of rabbit aorta in vivo are demonstrated.
Results:
Scout MRI with the transmit/receive antennae yielded a ≤10 cm cylindrical field-of-view, enabling subsequent targeted localization at ∼100 μm resolution in 10-50 s and/or 50 μm MRI in ∼2 min in vitro, and 100-300 μm MRI of the rabbit aorta in vivo.
Conclusion:
A simple, low-power, one-device approach to interventional MRI at 7T offers the potential of truly high-resolution MRI, while avoiding issues with external coil excitation and interactions at 7T.
