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Cancer immunotherapy: current status and future directions

Fumito Ito1, Alfred E Chang

  • 1Department of Surgery, University of Michigan Health System, 3410 Cancer Center/5932, 1500 East Medical Center Drive, Ann Arbor, MI 48109-5932, USA.

Surgical Oncology Clinics of North America
|September 10, 2013
PubMed

Better understanding of the underlying principles of tumor biology and immunology, enhanced by recent insights into the mechanisms of immune recognition, regulation, and tumor escape has provided new approaches for cancer immunotherapy. This article reviews the current status and future directions of cancer immunotherapy, with a focus on the recent encouraging results from immune-modulating antibodies and adoptive cell therapy.

Keywords:
Adoptive cell therapyCancer immunotherapyCancer vaccineImmune checkpointsImmune-modulating antibodies

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