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Updated: May 8, 2026
Adaptation of Semiautomated Circulating Tumor Cell (CTC) Assays for Clinical and Preclinical Research Applications
Published on: February 28, 2014
Markers of circulating breast cancer cells
Eunice López-Muñoz1, Manuel Méndez-Montes
1Departamento de Genética Médica, Unidad Médica de Alta Especialidad, Hospital de Gineco Obstetricia, No. 4, Dr. Luis Castelazo Ayala, IMSS, Colonia Tizapan San Angel, México, DF. astridkaryme2001@yahoo.com.mx
Abstract:
The detection of circulating tumor cells (CTC) aids in diagnosis of disease, prognosis, disease recurrence, and therapeutic response. The molecular aspects of metastasis are reviewed including its relevance in the identification and characterization of putative markers that may be useful in the detection thereof. Also discussed are methods for CTC enrichment using molecular strategies. The clinical application of CTC in the metastatic disease process is also summarized.
