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Banking human induced pluripotent stem cells: lessons learned from embryonic stem cells?
Glyn N Stacey1, Jeremy M Crook, Derek Hei
1National Institute for Biological Standards and Control a centre of the MHRA, South Mimms, Hertfordshire EN6 3QG, UK.
Cell Stem Cell
|October 8, 2013
Summary
Human embryonic stem cell networks provide accessible, quality-controlled cell lines. This study recommends engaging these networks to establish similar resources for induced pluripotent stem cells distribution and collection.
Area of Science:
- Stem cell biology
- Regenerative medicine
- Biotechnology
Background:
- Established human embryonic stem cell (hESC) banking networks have improved global researcher access to well-characterized cell lines.
- These networks ensure quality control and broad accessibility of critical stem cell resources.
Purpose of the Study:
- To provide recommendations for leveraging existing hESC networks.
- To guide the development of similar infrastructure for induced pluripotent stem cells (iPSCs).
- To facilitate the collection and distribution of iPSCs.
Main Methods:
- Analysis of existing hESC network models.
- Development of strategic recommendations based on established practices.
- Proposal for engaging current stem cell banking networks.
Main Results:
- Identification of key success factors from hESC networks.
- Framework for adapting hESC network models to iPSCs.
- Strategies for efficient iPSC collection and distribution.
Conclusions:
- Existing hESC networks offer a valuable blueprint for iPSC resource development.
- Engaging these networks can accelerate the establishment of robust iPSC distribution systems.
- Standardized approaches are crucial for ensuring the quality and accessibility of iPSCs for research.
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