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Updated: May 7, 2026

Capturing Actively Produced Microbial Volatile Organic Compounds from Human-Associated Samples with Vacuum-Assisted Sorbent Extraction
Published on: June 1, 2022
A glance at achievements in the coupling of headspace and direct immersion single-drop microextraction with
Lívia Kocúrová1, Ioseph S Balogh, Vasil Andruch
1Department of Analytical Chemistry, Pavol Jozef Šafárik University in Košice, Slovak Republic.
Abstract:
The present article offers a glance at achievements in single-drop microextraction(SDME), with a focus on the two most commonly used modes of this technique: headspace and direct immersion. Factors affecting SDME, such as the pH and ionic strength of the sample solution, the stirring rate, and the extraction time are briefly summarized. The requirements for the acceptor phase and the influence of the sampling temperature are presented. In addition, the potential of the application of microwave and ultrasonic energy in SDME is also discussed. Examples of the application of the headspace and direct immersion modes of SDME are given in a table as additional Supporting Information.
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