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Isolation and Genome Analysis of Single Virions using 'Single Virus Genomics'
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Tracking viral genomes in host cells at single-molecule resolution

I-Hsuan Wang1, Maarit Suomalainen, Vardan Andriasyan

  • 1Institute of Molecular Life Sciences, University of Zürich, CH-8057 Zurich, Switzerland; Molecular Life Sciences Graduate School, ETH and University of Zürich, CH-8057 Zurich, Switzerland.

Cell Host & Microbe
|October 22, 2013
PubMed
Summary

Researchers developed a new method to track viral DNA (vDNA) in single cells. This technique visualizes viral DNA trafficking, revealing nuclear import as a key bottleneck for adenovirus infection.

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