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Sphincter of Oddi dysfunction: an evidence-based review
Abdul Rehman1, John Affronti, Satish Rao
1Department of Medicine, Georgia Regents University, Medical College of Georgia, Section of Gastroenterology and Hepatology, 1120 15th St-BBR2538, Augusta, GA, 30912, USA.
Expert Review of Gastroenterology & Hepatology
|October 29, 2013
Summary
Sphincter of Oddi dysfunction causes biliary pain and pancreatitis. This review clarifies diagnostic and therapeutic approaches for this controversial condition, offering an evidence-based summary.
Area of Science:
- Gastroenterology and Hepatology
- Biliary Medicine
Background:
- Sphincter of Oddi dysfunction (SOD) is a painful syndrome.
- It presents as recurrent biliary pain or idiopathic pancreatitis.
- SOD remains controversial due to limited long-term controlled studies.
Purpose of the Study:
- To provide an evidence-based summary of current diagnostic and therapeutic approaches for SOD.
- To clarify the state-of-the-art in managing SOD.
- To address the controversies surrounding SOD's natural history and treatment outcomes.
Main Methods:
- Literature review of diagnostic modalities for SOD.
- Analysis of therapeutic approaches and treatment outcomes for SOD.
- Evidence-based synthesis of current knowledge on SOD.
Main Results:
- Current diagnostic criteria and methods for SOD are presented.
- Various therapeutic options, including medical and interventional, are discussed.
- Treatment outcomes and their variability are highlighted.
Conclusions:
- Clarification of the diagnostic and therapeutic landscape for SOD.
- Emphasis on the need for further controlled studies to define SOD's natural history and optimize treatment.
- Improved understanding to guide clinical decision-making for patients with SOD.
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