Related Experiment Video
Updated: May 6, 2026
07:45
Electrophoretic Crystallization of Ultrathin High-performance Metal-organic Framework Membranes
Published on: August 16, 2018
9.7K
Self-standing mesoporous membranes toward highly selective molecular transportation
Yusuke Yamauchi1, Tatsuo Kimura
1World Premier International (WPI) Research Center for Materials Nanoarchitectonics (MANA), National Institute for Materials Science (NIMS), 1-1 Namiki, Tsukuba, Ibaraki 305-0044, Japan. Yusuke.Yamauchi@nims.go.jp.
Chemical Communications (Cambridge, England)
|October 31, 2013
Summary
Researchers created advanced mesoporous membranes by infusing silica into cellulose filters. These uniform membranes enable precise, nanometer-level separation and rapid transport of biomolecules based on size.
Area of Science:
- Materials Science
- Nanotechnology
- Biotechnology
Background:
- Cellulose membrane filters are widely used but lack precise size-selectivity for biomolecules.
- Developing advanced filtration materials is crucial for biomolecule separation and purification.
Purpose of the Study:
- To fabricate self-standing, crack-free composite membranes with ordered mesoporous silica.
- To achieve highly size-selective and rapid transport of biomolecules.
Main Methods:
- Full infiltration of ordered mesoporous silica precursors into cellulose membrane filters.
- Optimizing fabrication conditions to minimize cracks and voids.
- Utilizing the uniform mesoporous structure for size-based separation.
Main Results:
- Successfully fabricated crack-free composite mesoporous membranes.
- Achieved highly size-selective separation of biomolecules at the nanometer level.
- Demonstrated rapid transportation of biomolecules through the uniform membrane structure.
Conclusions:
- The developed composite mesoporous membranes offer precise nanometer-level size-selectivity for biomolecules.
- These membranes provide a promising platform for advanced biomolecule separation and purification applications.
More Related Videos
Related Concept Videos
01:44The Significance of Membrane Transport
24.5K
The transport of solutes across the cell membrane is essential for metabolic processes, like maintaining cell size and volume, generating the action potential, exchanging nutrients and gases, etc. Membrane transport can be either passive or active. It can be simple diffusion, facilitated, or mediated transport aided by transport proteins such as transporters and channels.
Transporters facilitate either an active or passive movement of solutes. They can allow a single-molecule transport down its...
Transporters facilitate either an active or passive movement of solutes. They can allow a single-molecule transport down its...
24.5K
01:15Potentiometry: Membrane Electrodes
2.3K
Membrane electrodes, also known as p-ion electrodes, use membranes that selectively interact with free analyte ions, generating a potential difference across the membrane. The resulting membrane potential, known as the asymmetry potential, is not zero even when analyte concentrations on both sides of the membrane are equal. The membrane's response is typically not selective to a single analyte but proportional to the concentration of all ions in the sample solution capable of interacting at...
2.3K
01:16Facilitated Diffusion
1.7K
The plasma membrane, a critical structure in cellular biology, houses an array of transporters, or carrier proteins, interspersed within its lipid bilayer. These proteins play a crucial role in solute transport through facilitated diffusion, a form of passive diffusion that uses transporters to move the molecules across the membrane.
In this process, substrates such as organic compounds and ions interact with a transporter on one side, triggering conformational changes in proteins that enable...
In this process, substrates such as organic compounds and ions interact with a transporter on one side, triggering conformational changes in proteins that enable...
1.7K
01:24Cellular Membranes and Drug Transport
2.1K
Drugs must traverse multiple biological barriers, such as multi-layered skin, single-layered intestinal epithelium, and the plasma membrane, to reach their target sites within the body. The plasma membrane, a highly structured composite of phospholipids, carbohydrates, and proteins, is the cell's protective boundary, facilitating selective substance exchange.
Phospholipids arrange themselves into a bilayer, with hydrophilic heads oriented outward and hydrophobic tails facing inward.
Phospholipids arrange themselves into a bilayer, with hydrophilic heads oriented outward and hydrophobic tails facing inward.
2.1K
01:24What are Membranes?
8.5K
8.5K
01:18Detergent Purification of Membrane Proteins
5.5K
Detergents are used to purify the integral proteins of the membrane. The hydrophobic portion of the detergent can replace membrane phospholipids while solubilizing the membrane proteins. When detergent monomers reach a specific concentration in a solution called critical micelle concentration (CMC), they form micelles. Above CMC, the concentration of the detergent monomers remains in equilibrium with the micelle. The number of detergent monomers present in the CMC varies for each detergent, and...
5.5K