Polypoidal choroidal vasculopathy - a type I polypoidal subretinal neovasculopathy
1Division of Ophthalmology, Department of Surgery, University of Hawaii John A Burns School of Medicine, Honolulu, Hawaii; Retina Consultants of Hawaii, Honolulu, Hawaii, The Retina Center at Pali Momi, An Affiliation of Hawai'i Pacific Health, USA.
The Open Ophthalmology Journal
|November 23, 2013
Summary
Polypoidal choroidal vasculopathy (PCV) can develop in the other eye years later. This subretinal neovascularization responded well to high-dose ranibizumab treatment, supporting PCV as a polypoidal neovasculopathy.
Area of Science:
- Ophthalmology
- Retinal Vascular Diseases
Background:
- Polypoidal choroidal vasculopathy (PCV) is a subtype of age-related macular degeneration.
- PCV is characterized by abnormal blood vessels and polyp-like structures under the retina.
Purpose of the Study:
- To investigate the nature of PCV as a subretinal neovascularization.
- To evaluate the efficacy of high-dose ranibizumab in treating new-onset PCV.
Main Methods:
- Indocyanine green (ICG) angiography to visualize choroidal vasculature.
- Optical coherence tomography (OCT) to assess the location of neovascularization.
- Treatment with high-dose ranibizumab (2.0 mg).
Main Results:
- New onset of polypoidal subretinal neovascular membrane developed in the contralateral eye 13 years after initial PCV treatment.
- ICG angiography confirmed PCV as a subretinal neovascularization, not a choroidal abnormality.
- OCT showed the polypoidal complex located above Bruch's membrane and beneath the retinal pigment epithelium.
- High-dose ranibizumab led to excellent polyp closure and regression of the vascular network.
Conclusions:
- PCV represents a polypoidal neovasculopathy (PNV).
- PCV can manifest as new-onset subretinal neovascularization in the contralateral eye.
- High-dose ranibizumab is an effective treatment for PCV.
Keywords:
Subretinal neovascularizationbranching vascular networkmacular edema.polypoidal choroidal vasculopathyranibizumabserous retinal detachmentMore Related Videos
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