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Updated: May 5, 2026

Clinical Application of Single-Surgeon, Three-Port, Laparoscopic Resection for Colorectal Cancer with Natural Orifice Specimen Extraction
Published on: March 24, 2023
Controversies in laparoscopy for colon and rectal cancer
Kellie L Mathis1, Heidi Nelson
1Division of Colon and Rectal Surgery, Mayo Clinic, 200 First Street Southwest, Rochester, MN 55905, USA.
Abstract:
There is sufficient level I evidence to support and even recommend laparoscopy as the surgical modality of choice for colon cancer resection. Laparoscopy offers improved short-term outcomes and at least equivalent long-term oncologic outcomes when compared with open resection. Laparoscopic rectal cancer surgery remains investigational. Short-term results from a large multinational randomized trial suggest that laparoscopy is not inferior to open total mesorectal excision with regard to completeness of resection and short-term morbidity and mortality. It is necessary to await the long-term oncologic results of current studies before embracing laparoscopic proctectomy for rectal cancer.
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