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The role of complement in tumor growth

Ruben Pio1, Leticia Corrales, John D Lambris

  • 1Oncology Division (CIMA), and Department of Biochemistry and Genetics (School of Science), University of Navarra, Pamplona, Spain, rpio@unav.es.

Advances in Experimental Medicine and Biology
|November 26, 2013
PubMed
Summary

Complement activation, a key immune response, traditionally fights cancer. However, cancer cells exploit it, and complement may even promote tumor growth in chronic inflammation, requiring new therapeutic strategies.

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