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Updated: May 5, 2026

Chemotherapy-induced Vascular Toxicity - Real-time In vivo Imaging of Vessel Impairment
Published on: January 7, 2015
An approach to chemotherapy-associated toxicity
Zhanna Livshits1, Rama B Rao, Silas W Smith
1Weill Cornell Medical College, New York Presbyterian Hospital, 525 East 68th Street, New York, NY 10065, USA.
Chemotherapy affects multiple organ systems, making adverse effects difficult to distinguish from illness. This review details drug toxicities, management, and emergency interventions for chemotherapy complications, including rare intrathecal medication errors.
Area of Science:
- Oncology
- Pharmacology
- Emergency Medicine
Background:
- Chemotherapy's impact on organ systems can mimic cancer progression or other illnesses.
- Differentiating drug toxicity from disease sequelae is clinically challenging.
- Intrathecal medication errors present severe neurological risks requiring urgent care.
Purpose of the Study:
- To provide a comprehensive overview of common chemotherapeutic agents.
- To detail drug indications, organ-specific adverse effects, and toxicity management.
- To highlight emergency department strategies for chemotherapy-related complications and intrathecal errors.
Main Methods:
- Literature review of chemotherapeutic drugs and their toxicities.
- Compilation of management guidelines for common adverse events.
- Emphasis on emergency protocols for medication errors and supportive care.
Main Results:
- Chemotherapeutic agents exhibit diverse organ system toxicities.
- Effective management strategies exist for common chemotherapy side effects.
- Prompt intervention is critical for intrathecal medication errors.
Conclusions:
- Understanding chemotherapy's organ system effects is crucial for accurate diagnosis.
- Standardized management protocols improve patient outcomes.
- Emergency departments must be prepared for acute chemotherapy-induced toxicities and errors.
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