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Synthesis of Near-Infrared Emitting Gold Nanoclusters for Biological Applications
Published on: March 22, 2020
The relationship between DNA sequences and oligonucleotide-templated silver nanoclusters and their fluorescence
1State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin, 130022 (P. R. China); Graduate School of the Chinese Academy of Sciences, Beijing, 100039 (P. R. China), Fax: (+86) 431-85689711.
Abstract:
A novel approach was developed to study the relationship between DNA sequences and DNA-templated silver nanoclusters (DNA-Ag NCs) in detail by using an ordinary DNA strand as an example. Three kinds of Ag NCs are formed by using the DNA strand as a scaffold. By dividing the DNA template into several parts according to their different affinities to Ag(+) , it was found that the fluorescence properties of DNA-Ag NCs are related to not only the sequences but also to the position of different parts in the template, which provides a more efficient approach to obtain DNA-Ag NCs with required photoluminescence properties and may ultimately contribute to the targeted synthesis of DNA-Ag NCs.

