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Updated: May 4, 2026

Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation
Published on: August 8, 2025
Transapical transcatheter off-pump aortic valve implantation
Jörg Kempfert1, Sven Lehmann, Axel Linke
1Department of Cardiac Surgery, Heartcenter University of Leipzig, Germany.
Transapical aortic valve implantation (TA-AVI) offers a minimally invasive, beating-heart approach for high-risk patients. This novel technique shows promise for elderly individuals, demonstrating good outcomes with low stroke risk.
Area of Science:
- Cardiovascular Surgery
- Interventional Cardiology
- Medical Devices
Background:
- Aortic valve implantation (AVI) is crucial for treating aortic stenosis.
- Minimally invasive techniques are sought to reduce risks in high-risk patients.
- Transapical aortic valve implantation (TA-AVI) presents a novel off-pump approach.
Purpose of the Study:
- To describe the technique of transapical aortic valve implantation (TA-AVI).
- To evaluate the feasibility and initial outcomes of TA-AVI in high-risk patients.
- To assess the safety profile, including stroke risk, of this minimally invasive procedure.
Main Methods:
- TA-AVI performed as a beating-heart, off-pump procedure.
- Utilized an antegrade implantation technique with oversizing and direct access.
- Employed fluoroscopic and echocardiographic guidance with rapid ventricular pacing.
Main Results:
- Successful implantation of stent-based transcatheter xenografts.
- Procedure performed with direct access and accurate positioning.
- Associated with good outcomes and minimal stroke risk in selected patients.
Conclusions:
- TA-AVI is a promising minimally invasive alternative for elderly, high-risk patients.
- The technique allows for off-pump valve implantation with accurate stent-graft placement.
- Early results suggest favorable outcomes and a low risk of stroke.
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