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Whole eye axial biometry during accommodation using ultra-long scan depth optical coherence tomography
Jianguang Zhong1, Aizhu Tao2, Zhe Xu2
1Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida; Hangzhou First People's Hospital, Zhejiang, China.
American Journal of Ophthalmology
|February 4, 2014
Summary
This study shows that eye biometry changes during accommodation, with decreased anterior chamber depth and vitreous length, and increased lens thickness and axial length. Ultra-long scan depth optical coherence tomography (UL-OCT) is suitable for these measurements.
Area of Science:
- Ophthalmology
- Biomedical Optics
- Ocular Physiology
Background:
- Accommodation is a complex physiological process involving changes in ocular structures.
- Accurate measurement of ocular biometry during accommodation is crucial for understanding visual function and developing optical corrections.
Purpose of the Study:
- To investigate dynamic changes in whole eye axial biometry during accommodation.
- To evaluate the utility of ultra-long scan depth optical coherence tomography (UL-OCT) for measuring ocular biometry during accommodation.
Main Methods:
- A prospective, observational case series involving 21 adult subjects.
- Ocular biometry was measured using UL-OCT under relaxed (0 D) and accommodative (+6 D) states.
- Measurements included central corneal thickness, anterior chamber depth, lens thickness, vitreous length, and axial length.
Main Results:
- Accommodation significantly altered whole eye axial biometry.
- Anterior chamber depth decreased (3.128 ± 0.305 mm to 2.961 ± 0.298 mm) and lens thickness increased (3.723 ± 0.237 mm to 3.963 ± 0.234 mm).
- Vitreous length decreased (17.129 ± 0.864 mm to 17.057 ± 0.848 mm) and axial length increased (24.519 ± 0.917 mm to 24.545 ± 0.915 mm) during accommodation.
Conclusions:
- Whole eye axial biometry undergoes significant changes during accommodation.
- UL-OCT is a suitable and effective method for comprehensive ocular biometry measurements during accommodation.
