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Updated: May 2, 2026

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Subcutaneous Trigeminal Nerve Field Stimulation for Refractory Facial Pain
Published on: May 10, 2017
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Supraorbital and supratrochlear stimulation for trigeminal autonomic cephalalgias
Julien Vaisman1, Edrick Lopez, Nicholas K Muraoka
1Department of Physical Medicine and Rehabilitation, Harvard Medical School, Boston, MA, USA, jvaisman@painandwellnesscenter.com.
Current Pain and Headache Reports
|February 25, 2014
Summary
Trigeminal autonomic cephalalgias (TAC) presents difficult treatment challenges. This review explores conventional and novel neuromodulation techniques, including targeting specific trigeminal nerve branches, for severe pain relief.
Area of Science:
- Neurology
- Pain Medicine
- Neurosurgery
Background:
- Trigeminal autonomic cephalalgias (TAC) are rare primary headache disorders.
- Patients often experience severe, refractory pain with limited treatment options.
Purpose of the Study:
- To review conventional pharmacologic treatments for TAC.
- To explore emerging neuromodulation techniques as alternative, less invasive treatments for TAC.
Main Methods:
- Review of existing literature on pharmacologic and neuromodulation therapies for TAC.
- Discussion of neuromodulation techniques adapted from migraine treatment.
- Focus on targeting supratrochlear and supraorbital nerves.
Main Results:
- Conventional treatments for TAC are often insufficient for severe cases.
- Neuromodulation offers promising alternative strategies.
- Targeting specific trigeminal nerve branches shows potential.
Conclusions:
- Neuromodulation techniques represent a significant advancement in managing refractory TAC.
- Targeted nerve stimulation provides a less invasive therapeutic avenue.
- Further research into neuromodulation for TAC is warranted.

