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Updated: May 2, 2026

Employing the Forced Oscillation Technique for the Assessment of Respiratory Mechanics in Adults
Published on: February 9, 2022
Reference values for Japanese children's respiratory resistance using the LMS method.
Satomi Hagiwara1, Hiroyuki Mochizuki2, Reiko Muramatsu1
1Department of Pediatrics, Gunma University Graduate School of Medicine, Gunma, Japan.
Standard respiratory resistance (Rrs) values were established for healthy Japanese children using impulse oscillometry (IOS). These findings provide crucial reference data for diagnosing and managing pediatric asthma.
Area of Science:
- Pediatric Pulmonology
- Respiratory Physiology
Background:
- The forced oscillation technique (FOT) is valuable for assessing pediatric pulmonary function, particularly in children with asthma.
- Standard respiratory resistance (Rrs) values for Asian school children are not well-established.
- Impulse oscillometry (IOS) is a type of FOT used in this study.
Purpose of the Study:
- To determine standard respiratory resistance (Rrs) values in healthy Japanese elementary and junior high school children.
- To establish normative data for Rrs using impulse oscillometry (IOS).
Main Methods:
- A total of 795 healthy Japanese children (ages 6-15) participated.
- Respiratory resistance (Rrs) was measured using IOS in 537 children.
- Regression analyses were performed using age, height, weight, and obesity as variables.
Main Results:
- Respiratory resistance parameters (Rrs at 5Hz, Rrs at 20Hz, and R5-R20) showed the strongest correlation with height.
- All measured Rrs parameters decreased as children's height increased.
- Standardized Rrs curves were developed based on height using the LMS method.
Conclusions:
- The generated standard Rrs curves can aid in the diagnosis of respiratory conditions in children.
- These reference curves may assist in evaluating the effectiveness of asthma management in pediatric populations.
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