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Related Concept Videos

Jaundice01:25

Jaundice

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Jaundice, or icterus, is the yellow discoloration of the skin, sclerae, and mucous membranes. It happens when plasma bilirubin levels rise above 2.5-3 mg/dL, leading to bilirubin deposition in tissue.Bilirubin is a byproduct of hemoglobin degradation. In macrophages, hemoglobin breaks down into globin and heme. Globin is converted into amino acids, while heme is turned into biliverdin by heme oxygenase, which is then reduced to unconjugated bilirubin by biliverdin reductase.Unconjugated...
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Cholecystitis01:20

Cholecystitis

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Cholecystitis is inflammation of the gallbladder, most commonly caused by obstruction of the cystic duct. This blockage prevents bile from draining, leading to gallbladder distension, inflammation, and potentially serious complications. This condition may present acutely or chronically and can happen with or without gallstones.EtiologyAbout 95% of cholecystitis cases are calculous, caused by gallstones blocking the cystic duct, leading to bile accumulation and inflammation of the gallbladder...
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Diseases of the Liver and Gallbladder01:26

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Liver and gallbladder diseases are a significant health concern, with prominent conditions including cirrhosis, hepatitis, non-alcoholic fatty liver disease (NAFLD), and gallstones. Jaundice is a common manifestation of liver and biliary disease.
Cirrhosis is characterized by the scarring of hepatic lobules in the liver, which are replaced by fibrous tissue, affecting the liver's normal functioning. NAFLD, on the other hand, is caused by an excessive build-up of fat in the liver, not...
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Hepatic Drug Excretion: Influencing Factors01:16

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The biliary system of the liver, crucial for bile secretion and drug excretion, comprises intrahepatic bile ducts that merge to form the common hepatic duct. This duct, carrying hepatic bile, combines with the cystic duct, draining the gallbladder and forming the common bile duct, which empties into the duodenum. Bile, produced by hepatic cells lining the bile canaliculi, is composed primarily of water, bile salts, pigments, electrolytes, and lesser amounts of cholesterol and fatty acids. Bile...
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The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
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DefinitionHepatic encephalopathy is a reversible neurologic syndrome that results from advanced liver dysfunction or portosystemic shunting. It leads to disturbances in cognition, behavior, and motor function due to the brain’s exposure to gut-derived toxins that the liver fails to detoxify.EtiologyThis condition develops either in the setting of acute fulminant hepatitis or progressively during chronic liver disease, such as cirrhosis and portal hypertension. Portosystemic...
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Huge trichobezoar causing obstructive jaundice.

Ankit Verma1, Sourabh Sharma, Gaurav Tyagi

  • 1Department of General Surgery, Sawai Man Singh Hospital, Jaipur, Rajasthan, India.

BMJ Case Reports
|March 1, 2014
PubMed
Summary
This summary is machine-generated.

Trichobezoars, hair masses in the GI tract, can cause serious symptoms like jaundice. This case highlights the importance of considering psychiatric conditions in patients with trichobezoars.

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Area of Science:

  • Gastroenterology
  • Psychiatry
  • Surgical Case Report

Background:

  • Trichobezoars are masses of ingested hair or hair-like fibers, often linked to psychiatric disorders.
  • Their clinical presentation can be varied, posing diagnostic challenges.

Observation:

  • A 29-year-old woman presented with obstructive jaundice and a palpable upper abdominal mass.
  • Psychiatric evaluation revealed a diagnosis of post-traumatic stress disorder.

Findings:

  • Exploratory laparotomy confirmed a large trichobezoar as the cause of obstruction.
  • Surgical removal of the trichobezoar was successfully performed.

Implications:

  • This case underscores the association between trichobezoars and psychiatric conditions, particularly in young women.
  • Prompt diagnosis and surgical intervention are crucial for managing obstructive trichobezoars.
  • Multidisciplinary management involving surgical and psychiatric teams is essential for comprehensive patient care.