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Updated: May 2, 2026

Imine Metathesis by Silica-Supported Catalysts Using the Methodology of Surface Organometallic Chemistry
Published on: October 18, 2019
Synergistic-cooperative combination of enamine catalysis with transition metal catalysis
Yongming Deng1, Siddhartha Kumar, Hong Wang
1Department of Chemistry and Biochemistry, Miami University, Oxford, OH 45056, USA. wangh3@miamioh.edu.
Abstract:
Synergistic-cooperative combination of enamine catalysis with transition metal catalysis is an emerging and exciting field aiming to achieve organic transformations that cannot be accomplished by individual catalysis. The biggest obstacle in this field lies in the catalyst incompatibility arising from Lewis acid-Lewis base interactions. Several strategies including soft/hard combination of a Lewis acid and a Lewis base, the utilization of a chelating ligand, and mixing an ammonium salt with a Lewis acid have been developed to solve the incompatibility problem. A number of new reactions and new reaction modes have been discovered using these strategies. In this review article, we aim to highlight these new discoveries found in the literature.
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