Polypoidal choroidal vasculopathy: an update on therapeutic approaches

Area of Science:

• Ophthalmology
• Retinal Vascular Diseases
• Choroidal Vasculature

Background:

• Polypoidal choroidal vasculopathy (PCV) is a distinct retinal disease characterized by polypoidal lesions in the choroidal vasculature.
• It is more common in Asian and Black populations and can be mistaken for neovascular age-related macular degeneration.
• Symptoms include subretinal hemorrhage, pigment epithelial detachment, and retinal detachment, leading to potential vision loss.

Purpose of the Study:

• To provide an updated review of current therapeutic options for symptomatic polypoidal choroidal vasculopathy (PCV).
• To highlight recent research and treatment advancements in managing PCV over the past two years.

Main Methods:

• Literature review focusing on recent studies (past two years) concerning PCV treatments.
• Analysis of various therapeutic modalities including thermal laser, photodynamic therapy (PDT), anti-VEGF therapy, and combination treatments.

Main Results:

• The review synthesizes findings on the efficacy and application of different treatment strategies for PCV.
• Recent studies provide further insights into the evolving landscape of PCV management.

Conclusions:

• Symptomatic PCV requires timely treatment to prevent irreversible visual impairment.
• A range of treatment options are available, with ongoing research refining their use and effectiveness.