[Detection of antibodies to Rickettsia prowazekii using 3 serologic tests]

Commercial antigens of R. prowazekii may be used for the diagnosis of the typhus group rickettsiosis by the new solid-phase indirect enzyme immunoassay (SPI EIA). High sensitivity of the test makes the diagnosis of rickettsioses more effective and ensures an earlier detection of typhus patients. The authors have employed SPI EIA modification with polyethylene glycol, permitting a change in the incubation regimen (20 degrees C instead of 37 degrees C) and more rapid reaction; this recommends the method for laboratory and field practice. The possibility of a visual assessment of the test results also recommends it for wide practice.