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Developmental Toxicity Assay Based on Real-Time Monitoring of Fibroblast Growth Factor Signal Disruption in Human Induced Pluripotent Stem Cells
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Studies on improving the embryonic stem cell test for an assessment of neuroembryotoxic effects

N Miechielsen1, F Merz1, A Heselich1

  • 1Department of Chemical Engineering and Biotechnology, University of Applied Sciences , Darmstadt, Schnittspahnstrasse 12, 64287 Darmstadt.

Journal of Stem Cells & Regenerative Medicine
|April 3, 2014
PubMed
Abstract

No abstract available in PubMed .

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Embryonic stem (ES) cells were first discovered in mice in 1981 by Martin Evans. In 1998, James Thomson identified a method to isolate embryonic stem cells from humans. Human embryonic stem cells (hESCs) are obtained from 3-5 day old embryos that remain unused after an in vitro fertilization procedure.
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