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Updated: May 1, 2026

Investigating Pain-Related Avoidance Behavior using a Robotic Arm-Reaching Paradigm
Published on: October 3, 2020
An epigenetic way to forget those painful moments
Sören Diegelmann1, Simon G Sprecher1
1Department of Biology, Institute of Zoology, Chemin du Musée 10, CH-1700 Fribourg, Switzerland.
Abstract:
Traumatic experience can be overwhelming, thus erasing associated memories is desirable. Although exposure-based and reconsolidation methods have been developed for recently acquired associations, treatments to modify more distant memories are rare. Focusing on HDAC2 inhibition during reconsolidation, Gräff and colleagues recently demonstrated an epigenetic means to attenuate remote fear memory.
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