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Long-lasting permethrin impregnated uniforms: A randomized-controlled trial for tick bite prevention.
Meagan F Vaughn1, Sheana Whelan Funkhouser1, Feng-Chang Lin2
1Department of Epidemiology, Gillings School of Global Public Health, Chapel Hill.
American Journal of Preventive Medicine
|April 22, 2014
Summary
Long-lasting permethrin-impregnated uniforms significantly reduced tick bites for outdoor workers. This protective clothing is highly effective for at least one year, enhancing occupational safety against tick-borne diseases.
Area of Science:
- Occupational Health
- Environmental Entomology
- Preventive Medicine
Background:
- Outdoor workers face high tick-borne disease risk due to habitat exposure.
- Adherence to standard tick bite prevention methods is often inadequate.
- Factory-applied permethrin clothing offers long-lasting protection, but field validation is needed.
Purpose of the Study:
- To assess the effectiveness of permethrin-treated uniforms in preventing tick bites.
- Evaluate long-term protection in North Carolina outdoor workers.
Main Methods:
- A double-blind randomized controlled trial (RCT) involving outdoor workers.
- Comparison of factory-impregnated permethrin uniforms versus sham-treated uniforms.
- Data collection via weekly tick bite logs over two years.
Main Results:
- A total of 1,045 work-related tick bites were reported.
- Permethrin uniforms showed 82% effectiveness in year one (CI=0.66, 0.91).
- Effectiveness in year two was 34% (CI=-0.67, 0.74).
Conclusions:
- Permethrin-impregnated uniforms provide substantial tick bite prevention for at least one year.
- This intervention is effective alongside existing prevention strategies.
- The study supports the use of permethrin-treated clothing for occupational safety.

