Mast cell sarcoma: clinical management
Catherine R Weiler1, Joseph Butterfield1
1Program of Excellence in Mast Cell and Eosinophil Disorders, Division of Allergic Disease, Department of Internal Medicine, W-15 Mayo Building, 200 First Street Southwest, Rochester, MN 55905, USA.
Abstract:
Mast cell sarcoma is a disorder that results in abnormal mast cells as identified by morphology, special stains, and in some publications, c-kit mutation analysis. It affects animal species such as canines more commonly than humans. In humans it is a very rare condition, with variable clinical presentation. There is no standard therapy for the disorder. It can affect any age group. It is occasionally associated with systemic mastocytosis and/or urticaria pigmentosa. The prognosis of mast cell sarcoma in published literature is very poor in humans.
