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Updated: Apr 30, 2026

Comparison of Agreement and Accuracy using Binocular Wavefront Optometer with Autorefractor and Phoropter
Published on: September 16, 2025
Contrast sensitivity function after correcting residual wavefront aberrations during RGP lens wear.
Bi Yang1, Bo Liang, Longqian Liu
1*MS †PhD ‡MD Department of Optometry, West China School of Medicine, Sichuan University, Chengdu, Sichuan, China (BY, LL, ML, QL); Institute of Optics and Electronics, Chinese Academy of Sciences, Chengdu, Sichuan, China (BL, YD, HZ, Y Zhang); and Vision Research Lab, School of Life Sciences, University of Science and Technology of China, Hefei, China (Y Zhou).
Correcting wavefront aberrations with adaptive optics (AO) improved contrast sensitivity in keratoconic rigid gas permeable (RGP) lens wearers. However, AO correction did not significantly affect contrast sensitivity function (CSF) in myopic RGP lens wearers.
Area of Science:
- Ophthalmology
- Optometry
- Vision Science
Background:
- Rigid gas permeable (RGP) contact lenses are used to correct refractive errors and irregular astigmatism.
- Residual wavefront aberrations can persist despite RGP lens correction, potentially impacting visual quality.
- Contrast sensitivity function (CSF) is a key measure of visual performance.
Purpose of the Study:
- To evaluate the impact of correcting residual wavefront aberrations on the CSF in myopic and keratoconic subjects wearing RGP lenses.
- To determine if adaptive optics (AO) technology can enhance visual performance in these patient groups.
Main Methods:
- Seventeen myopic eyes and 20 keratoconic eyes, habitually corrected with RGP lenses, were studied.
- An adaptive optics (AO) system was used to compensate for residual aberrations.
- Contrast sensitivity was measured at various spatial frequencies (2-32 cycles per degree) with and without AO correction.
Main Results:
- In myopic subjects, AO correction showed no significant difference in CSF compared to no AO correction.
- In keratoconic subjects, AO correction significantly improved CSF at low (2 cpd) and intermediate (4, 8, 16 cpd) spatial frequencies.
- Contrast sensitivities were consistently higher with AO correction in keratoconic eyes.
Conclusions:
- Residual aberrations significantly degrade CSF at lower spatial frequencies in keratoconic RGP lens wearers.
- Wavefront aberration correction via AO does not significantly improve CSF in myopic RGP lens wearers.
- Advanced wavefront aberration correction techniques hold potential for improving visual outcomes in keratoconus patients.

