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High-calorie diet as a factor of prediabetes development in rats
T P Karpovets1, V V Konopelnyuk, T I Galenova
1Education-Scientific Center Institute of Biology, T. Shevchenko Kiev National University, Kyiv, Ukraine, Taras.karpovets@gmail.com.
Bulletin of Experimental Biology and Medicine
|April 29, 2014
Abstract:
We studied the key parameters of the development of prediabetic state in rats maintained on a high-calorie diet. It was found that long-term feeding a high-calorie diet increased blood concentration of glucose, glycosylated hemoglobin, and insulin and reduced the rate of glucose uptake in comparison with rats receiving standard ration.
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