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Updated: Apr 30, 2026

Murine Oropharyngeal Aspiration Model of Ventilator-associated and Hospital-acquired Bacterial Pneumonia
Published on: June 28, 2018
Adherence to institution-specific ventilator-associated pneumonia prevention guidelines
Hiroko Kiyoshi-Teo1, Michael D Cabana, Erika S Froelicher
1Hiroko Kiyoshi-Teo is a clinical assistant professor, School of Nursing, Oregon Health & Science University, Portland, Oregon. Michael Cabana is a professor of pediatrics, epidemiology and biostatistics, School of Medicine, University of California San Francisco, San Francisco, California. Erika Froelicher is a professor emerita, physiological nursing, School of Nursing, and Epidemiology & Biostatistics, School of Medicine, University of California San Francisco, San Francisco, California; and professor, Health Sciences, Sifa University, Izmir, Turkey. Mary Blegen is a professor emerita, School of Nursing, University of California San Francisco, San Francisco, California.
Nurses' positive attitudes are key to preventing ventilator-associated pneumonia (VAP). Fostering favorable views of VAP prevention guidelines significantly improves adherence to crucial patient care strategies.
Area of Science:
- Critical Care Medicine
- Infection Prevention
- Nursing Research
Background:
- Institution-specific guidelines exist to prevent ventilator-associated pneumonia (VAP).
- Guideline availability alone does not guarantee adherence to recommended VAP prevention strategies.
- Understanding factors influencing adherence is crucial for improving patient outcomes.
Purpose of the Study:
- To identify factors influencing adherence to VAP prevention guidelines.
- Focus on key interventions: oral hygiene, head-of-bed elevation, and spontaneous breathing trials.
- Explore user, guideline, and contextual factors impacting adherence.
Main Methods:
- Cross-sectional descriptive study involving 576 critical care nurses across 8 Northern California hospitals.
- Survey developed to assess facilitators and barriers to guideline adherence for VAP prevention.
- Analysis of user factors, guideline qualities, and contextual factors for potential relationships.
Main Results:
- Nurses generally reported positive attitudes and high adherence rates (always or most of the time).
- Adherence predictors varied by intervention, with user attitude being the strongest consistent predictor (OR, 3.49-4.75).
- Time availability (OR, 1.54) and prioritization (OR, 1.86) also significantly predicted adherence.
Conclusions:
- Nurses' positive attitude toward VAP prevention guidelines is the most consistent facilitator of adherence.
- Interventions to improve VAP prevention should focus on cultivating positive nurse attitudes.
- Addressing time and prioritization barriers may further enhance adherence to VAP prevention strategies.
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