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Updated: Apr 30, 2026
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Author Spotlight: Eco-friendly Photoluminescent Textile Authentication with Curcumin
Published on: December 22, 2023
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Curcumin
Maria L A D Lestari1, Gunawan Indrayanto1
1Faculty of Pharmacy, Airlangga University, Dharmawangsa Dalam, Surabaya, Indonesia.
Summary
This review explores curcuminoids, natural compounds from Curcuma species, detailing their stability, spectral properties, and analytical methods. Liquid chromatography-tandem mass spectrometry (LC-MS/MS) is recommended for analyzing curcuminoids in complex samples.
Area of Science:
- Phytochemistry
- Analytical Chemistry
- Pharmacology
Background:
- Curcuminoids, including curcumin, demethoxycurcumin, and bis-demethoxycurcumin, are key secondary metabolites in Curcuma species.
- Curcumin serves as a coloring agent and food additive, with recognized therapeutic potential.
Purpose of the Study:
- To comprehensively review the stability, spectroscopic characteristics, polymorphism, and analytical methodologies for curcuminoids.
- To summarize metabolite studies of curcumin and its related compounds.
- To recommend optimal analytical techniques for complex matrices.
Main Methods:
- Literature review of curcuminoid properties and analysis.
- Summary of spectroscopic techniques (UV, IR, Raman, MS, NMR).
- Evaluation of analytical methods for biological and non-biological samples.
Main Results:
- Curcuminoids exhibit varying stability in solutions.
- Distinct spectroscopic signatures aid in their identification and characterization.
- Liquid chromatography-tandem mass spectrometry (LC-MS/MS) is highlighted as a superior method for analyzing curcuminoids in complex matrices.
Conclusions:
- Understanding curcuminoid properties is crucial for their applications.
- Standardized analytical methods are essential for accurate quantification.
- LC-MS/MS offers high sensitivity and specificity for curcuminoid analysis.
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