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Is contrast medium osmolality a causal factor for contrast-induced nephropathy?

Andreas M Bucher1, Carlo N De Cecco2, U Joseph Schoepf3

  • 1Department of Radiology and Radiological Science, Medical University of South Carolina, 25 Courtenay Drive MSC 226, Charleston, SC 29425, USA ; Department of Diagnostic and Interventional Radiology, Johann Wolfgang Goethe University Hospital, 60590 Frankfurt am Main, Germany.

Biomed Research International
|May 7, 2014
PubMed
Summary

Contrast-induced nephropathy (CIN) pathophysiology remains unclear, but osmotic effects of contrast media (CM) are key. Lower osmolality CM offers minimal advantage, while osmotic diuresis may protect kidneys.

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