Effect of highly mineralized natural water on redox processes in HaCaT keratinocytes
N S Zaitseva1, A V Chechushkov, P M Kozhin
1Research Center of Clinical and Experimental Medicine, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk, Russia, natasha115@list.ru.
Bulletin of Experimental Biology and Medicine
|May 15, 2014
Abstract:
We studied ROS production by HaCaT keratinocytes, the state of transmembrane mitochondrial potential, and activation of transcription factor Nrf2 in response to brine exposure. It was demonstrated that this exposure induces rapid but moderate decrease in mitochondrial potential, stimulates ROS production, and leads to activation of transcription factor Nrf2.
