Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Hyperpnea and Hyperventilation01:25

Hyperpnea and Hyperventilation

4.0K
Hyperventilation refers to a higher-than-normal rate and depth of breathing, often associated with anxiety attacks. This excessive breathing surpasses the body's need to expel CO2, leading to a condition known as hypocapnia - an unusually low level of carbon dioxide in the blood. Hypocapnia can constrict cerebral blood vessels, reducing blood flow to the brain, which may result in dizziness or fainting. Early signs include tingling and muscle spasms in the hands and face, caused by falling...
4.0K
Measurement of Blood Pressure01:17

Measurement of Blood Pressure

4.0K
Assessing blood pressure is a standard procedure executed in virtually all medical environments. The method utilized today was established over a hundred years ago by an innovative Russian doctor, Dr. Nikolai Korotkoff. The soft ticking noise, known as Korotkoff sounds, heard while taking blood pressure readings results from turbulent blood flow within the vessels. The apparatus required for this procedure includes a sphygmomanometer, a blood pressure cuff attached to a gauge, and a...
4.0K
Acute Respiratory Failure-II01:21

Acute Respiratory Failure-II

1.8K
Type I Respiratory Failure, or hypoxemic respiratory failure, occurs when the partial pressure of oxygen (PaO2) in arterial blood falls below 60 mmHg while breathing room air without a corresponding increase in arterial carbon dioxide levels (PaCO2). This condition highlights a significant impairment in the lungs' capacity to oxygenate the blood.
The underlying physiological abnormalities that contribute to hypoxemic respiratory failure include:
1.8K
Heart Failure III: Clinical Manifestations01:26

Heart Failure III: Clinical Manifestations

1.1K
Heart failure (HF) manifests primarily as dyspnea, fatigue, and fluid retention, resulting in peripheral and pulmonary edema. Symptoms may vary depending on which ventricle is more affected, left or right.Left-Sided Heart FailureAlso known as left ventricular failure, this condition results from the left ventricle's inability to fill or eject sufficient blood into the systemic circulation. It leads to pulmonary congestion, which occurs when the left ventricle fails to eject blood effectively...
1.1K
Acute Respiratory Failure-IV01:23

Acute Respiratory Failure-IV

797
Respiratory failure can manifest suddenly or gradually, characterized by a rapid decline in PaO2 and a rapid rise in PaCO2. This situation indicates a severe respiratory problem that may quickly become a life-threatening emergency. One of the early signs of hypoxemic Acute Respiratory Failure (ARF) is a change in mental status due to the brain's sensitivity to oxygen levels and changes in acid-base balance. Symptoms such as restlessness, confusion, and agitation suggest inadequate oxygen...
797
Hypoxia01:23

Hypoxia

2.4K
Hypoxia is a medical condition characterized by an inadequate oxygen supply to body tissues. It typically manifests as a bluish discoloration of the skin and mucosae, especially in fair-skinned individuals, when hemoglobin (Hb) saturation drops below 75%.
Types of Hypoxia
There are four primary types of hypoxia, each resulting from a different cause:
1. Anemic hypoxia: This type occurs due to insufficient oxygen delivery caused by a lack of red blood cells (RBCs) or RBCs with abnormal or...
2.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Sleep-related breathing disorders beyond infancy following open spina bifida repair.

European journal of pediatrics·2026
Same author

Pulmonary and Ear-Nose-Throat Considerations in the Perioperative Period for Children with Medical Complexity.

Pediatric clinics of North America·2026
Same author

Initial Survival and Short-term Pulmonary Comorbidities in Infants With Congenital Diaphragmatic Hernia of Differing Indices of Social Determinants of Health.

Journal of pediatric surgery·2025
Same author

Randomised trial of home sleep apnoea testing compared to in-lab polysomnography for the evaluation of obstructive sleep apnoea in children: rationale and study protocol.

BMJ open·2025
Same author

Corrigendum to Diagnosis of post-hematopoietic stem cell transplant bronchiolitis obliterans syndrome in children: time for a rethink? Transplantation and Cellular Therapy. 2024 Aug;30(8):760-769.

Transplantation and cellular therapy·2025
Same author

Evaluating the Impact of the COVID-19 Pandemic on Pediatric Asthma Incidence.

The journal of allergy and clinical immunology. In practice·2025
Same journal

Non-Linear Dysanaptic Lung Growth in Patients With Post-Infectious Bronchiolitis Obliterans.

Pediatric pulmonology·2026
Same journal

Safety of Less Invasive Surfactant Administration in Preterm Infants: A Meta-Analysis.

Pediatric pulmonology·2026
Same journal

Early Oxygenation Trajectory and Noninvasive Ventilation Failure in Non-Immunocompromised Children With Pediatric ARDS.

Pediatric pulmonology·2026
Same journal

Pulmonary Exacerbations and Treatment in PCD: A Narrative Review.

Pediatric pulmonology·2026
Same journal

Asthma in Children With Congenital Lung Malformations: A Population-Based Case-Control Study.

Pediatric pulmonology·2026
Same journal

Long-Term Effect Of COVID-19 on Children's Lung Function: A Prospective Longitudinal Study.

Pediatric pulmonology·2026
See all related articles

Related Experiment Video

Updated: Apr 29, 2026

Tilt Testing with Combined Lower Body Negative Pressure: a "Gold Standard" for Measuring Orthostatic Tolerance
14:09

Tilt Testing with Combined Lower Body Negative Pressure: a "Gold Standard" for Measuring Orthostatic Tolerance

Published on: March 21, 2013

20.7K

Syncope at altitude: an enigmatic case.

Aliva De1, Sally L Davidson Ward

  • 1Division of Pediatric Pulmonology, Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, California.

Pediatric Pulmonology
|May 28, 2014
PubMed
Summary
This summary is machine-generated.

Recurrent fainting spells in a young boy at high altitudes were observed. This case explores potential causes beyond typical altitude sickness, aiding medical diagnosis.

Keywords:
altitude related disease in pediatricsneuro-cardiogenic syncopesyncope at altitude

More Related Videos

A Model to Simulate Clinically Relevant Hypoxia in Humans
09:54

A Model to Simulate Clinically Relevant Hypoxia in Humans

Published on: December 22, 2016

8.5K
Integration of Brain Tissue Saturation Monitoring in Cardiopulmonary Exercise Testing in Patients with Heart Failure
04:20

Integration of Brain Tissue Saturation Monitoring in Cardiopulmonary Exercise Testing in Patients with Heart Failure

Published on: October 1, 2019

5.1K

Related Experiment Videos

Last Updated: Apr 29, 2026

Tilt Testing with Combined Lower Body Negative Pressure: a "Gold Standard" for Measuring Orthostatic Tolerance
14:09

Tilt Testing with Combined Lower Body Negative Pressure: a "Gold Standard" for Measuring Orthostatic Tolerance

Published on: March 21, 2013

20.7K
A Model to Simulate Clinically Relevant Hypoxia in Humans
09:54

A Model to Simulate Clinically Relevant Hypoxia in Humans

Published on: December 22, 2016

8.5K
Integration of Brain Tissue Saturation Monitoring in Cardiopulmonary Exercise Testing in Patients with Heart Failure
04:20

Integration of Brain Tissue Saturation Monitoring in Cardiopulmonary Exercise Testing in Patients with Heart Failure

Published on: October 1, 2019

5.1K

Area of Science:

  • Pediatric Medicine
  • Altitude Physiology
  • Neurology

Background:

  • Syncope, or fainting, can have various underlying causes.
  • Altitude sickness typically presents with respiratory and neurological symptoms.

Observation:

  • A young male patient experienced recurrent episodes of syncope.
  • These episodes occurred specifically at elevated altitudes.

Findings:

  • The patient's presentation did not align with common symptoms of acute mountain sickness.
  • Differential diagnoses and potential etiologies for altitude-induced syncope were explored.

Implications:

  • This case highlights the importance of considering syncope in the differential diagnosis for individuals experiencing symptoms at high altitudes.
  • Further investigation into the pathophysiology of altitude-related syncope is warranted.
  • Clinicians should be aware of atypical presentations of altitude-related conditions.