Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Photoreceptors and Visual Pathways01:22

Photoreceptors and Visual Pathways

8.4K
At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category,...
8.4K
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

5.1K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
5.1K
Autoimmune Disorders01:29

Autoimmune Disorders

2.3K
Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
Concept and Mechanism of Autoimmune Diseases
The immune...
2.3K
Hypersensitivity Reactions: Immune-Complex Reactions01:19

Hypersensitivity Reactions: Immune-Complex Reactions

266
Type III hypersensitivity reactions occur when antigen–antibody complexes form and activate the complement system. Normally, these complexes help the clearance of antigens by phagocytes and red blood cells. However, when large numbers of immune complexes are present, they can deposit in tissues—particularly in the walls of blood vessels—leading to inflammation and tissue injury. These deposits trigger complement activation and neutrophil recruitment, resulting in serum...
266
Acne Infection01:27

Acne Infection

91
Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
91
Drug Toxicity: Allergic Reactions01:30

Drug Toxicity: Allergic Reactions

206
Drug-related allergies are immune-mediated responses triggered by the administration of pharmacological agents. These hypersensitivity reactions are classified based on the immune mechanisms involved. The four primary types—Type I, II, III, and IV—are mediated by different immunological pathways and exhibit distinct clinical manifestations.Type I Hypersensitivity/ IgE-Mediated Reactions: Immunoglobulin E (IgE) immediately mediates Type I hypersensitivity reactions. Upon initial...
206

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Measurements of sun sensitivity in five European countries confirm the relative nature of Fitzpatrick skin phototype scale.

Photodermatology, photoimmunology & photomedicine·2019
Same author

Polypharmacy and sun exposure: Implications for mitochondrial DNA deletions in skin.

Journal of photochemistry and photobiology. B, Biology·2017
Same author

Mitochondrial DNA deletion percentage in sun exposed and non sun exposed skin.

Journal of photochemistry and photobiology. B, Biology·2016
Same author

Case Report of Calciphylaxis Secondary to Calcium and Vitamin D<sub>3</sub> Supplementation.

Journal of cutaneous medicine and surgery·2016
Same author

Artificial White Light vs Daylight Photodynamic Therapy for Actinic Keratoses: A Randomized Clinical Trial.

JAMA dermatology·2016
Same author

Contact allergy in cheilitis.

International journal of dermatology·2015
Same journal

The Evidence Is In: Devices and Biologics Reshaping Modern Dermatology.

Dermatologic clinics·2026
Same journal

Energy-Based Devices for Body Contouring.

Dermatologic clinics·2026
Same journal

Microfocused Ultrasound with Visualization for Skin Tightening: Clinical Applications, Safety, and Technical Considerations.

Dermatologic clinics·2026
Same journal

Devices in Onychomycosis: A Status Update.

Dermatologic clinics·2026
Same journal

Acne Laser Devices in Dermatology.

Dermatologic clinics·2026
Same journal

Fractional Laser Therapy for Androgenetic Alopecia: Mechanisms, Clinical Evidence, and Practical Implementation.

Dermatologic clinics·2026
See all related articles

Related Experiment Video

Updated: Apr 28, 2026

Stimulation of Stem Cell Niches and Tissue Regeneration in Mouse Skin by Switchable Protoporphyrin IX-Dependent Photogeneration of Reactive Oxygen Species In Situ
10:05

Stimulation of Stem Cell Niches and Tissue Regeneration in Mouse Skin by Switchable Protoporphyrin IX-Dependent Photogeneration of Reactive Oxygen Species In Situ

Published on: May 8, 2020

1.8K

Photoaggravated disorders.

Susan M O'Gorman1, Gillian M Murphy2

  • 1Dermatology Department, Beaumont Hospital, Beaumont Road, Beaumont, Dublin 9, Ireland.

Dermatologic Clinics
|June 4, 2014
PubMed
Summary
This summary is machine-generated.

Photoaggravated skin disorders worsen with UV radiation exposure. Differentiating these conditions from similar photodermatoses and implementing photoprotection are key management strategies.

Keywords:
PhotoaggravatedPhotodermatosesPhotosensitivityUltraviolet radiation

More Related Videos

LED-Based In Vitro Screening for Assessing Photoactivable Molecules in Bacterial Photodynamic Inactivation
05:13

LED-Based In Vitro Screening for Assessing Photoactivable Molecules in Bacterial Photodynamic Inactivation

Published on: January 24, 2025

931
An In Vitro Approach to Photodynamic Therapy
04:53

An In Vitro Approach to Photodynamic Therapy

Published on: August 17, 2018

10.7K

Related Experiment Videos

Last Updated: Apr 28, 2026

Stimulation of Stem Cell Niches and Tissue Regeneration in Mouse Skin by Switchable Protoporphyrin IX-Dependent Photogeneration of Reactive Oxygen Species In Situ
10:05

Stimulation of Stem Cell Niches and Tissue Regeneration in Mouse Skin by Switchable Protoporphyrin IX-Dependent Photogeneration of Reactive Oxygen Species In Situ

Published on: May 8, 2020

1.8K
LED-Based In Vitro Screening for Assessing Photoactivable Molecules in Bacterial Photodynamic Inactivation
05:13

LED-Based In Vitro Screening for Assessing Photoactivable Molecules in Bacterial Photodynamic Inactivation

Published on: January 24, 2025

931
An In Vitro Approach to Photodynamic Therapy
04:53

An In Vitro Approach to Photodynamic Therapy

Published on: August 17, 2018

10.7K

Area of Science:

  • Dermatology
  • Photomedicine

Background:

  • Photoaggravated skin disorders are exacerbated by UV radiation.
  • Photoaggravation prevalence varies; common in lupus erythematosus, less so in psoriasis and atopic dermatitis.
  • Differentiating photoaggravation from conditions like polymorphous light eruption is crucial.

Purpose of the Study:

  • To highlight the significance of UV radiation in exacerbating certain skin conditions.
  • To emphasize the importance of distinguishing between primary photoaggravation and superimposed photodermatoses.
  • To outline essential management strategies for photoaggravated skin disorders.

Main Methods:

  • Review of clinical presentations and UV radiation impact on various skin disorders.
  • Analysis of diagnostic challenges in differentiating photoaggravated conditions from photodermatoses.
  • Discussion of treatment and management protocols.

Main Results:

  • Photoaggravation affects a significant portion of patients with conditions like lupus erythematosus.
  • A subset of patients with psoriasis and atopic dermatitis experience photoaggravation.
  • Polymorphous light eruption is a common photodermatosis that can mimic or coexist with photoaggravated disorders.

Conclusions:

  • Effective management requires accurate diagnosis, differentiating photoaggravation from other photodermatoses.
  • Disease-specific treatments should be prioritized.
  • Photoprotection, including behavioral changes, UV-protective clothing, and broad-spectrum sunscreen, is a cornerstone of managing photoaggravated conditions.