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Related Concept Videos

Blood Transfusion and Agglutination02:45

Blood Transfusion and Agglutination

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Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
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Blood Transfusion01:15

Blood Transfusion

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Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
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Fetal Circulation01:14

Fetal Circulation

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Fetal circulation is a unique system that facilitates the exchange of gases, nutrients, and waste products between the developing fetus and the mother. This intricate process takes place through a special organ called the placenta.
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...
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The ABO Blood Group01:12

The ABO Blood Group

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The ABO blood group system is a critical element of transfusion medicine, essential for determining blood compatibility in transfusions and organ transplants. It is based on specific antigens, or agglutinogens, present on the surface of red blood cells (RBCs) and corresponding antibodies, or agglutinins, in the blood plasma.
Antigens in the ABO Blood Group System
Antigens are substances that can trigger an immune response, leading to the production of antibodies. In the ABO blood group system,...
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Blood Typing01:10

Blood Typing

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Understanding an individual's blood group is a critical component of transfusion medicine. It ensures compatibility in blood transfusions, organ transplants, and even during pregnancy. Determining these blood groups involves the ABO and Rh blood typing systems, utilizing specific antigens and corresponding anti-sera to identify an individual's blood type.
Antigens are protein molecules that reside on the surface of red blood cells (RBCs). The ABO and Rh blood typing systems target...
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Rh Blood Group01:19

Rh Blood Group

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The Rhesus (Rh) antigen is crucial in determining blood groups and ensuring compatibility during blood transfusions.
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Related Experiment Video

Updated: Apr 28, 2026

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
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Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

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Blood transfusion in obstetrics.

A Nigam1, A Prakash1, P Saxena1

  • 1Department of Obstetrics and Gynecology, Lady Hardinge Medical College and Smt. Sucheta, Kriplani Hospital, New Delhi, India.

Kathmandu University Medical Journal (KUMJ)
|June 6, 2014
PubMed
Summary

Blood transfusions in obstetrics carry risks, with reactions occurring in 4% of cases. This article discusses transfusion principles, alternatives, and guidelines for safe obstetric blood use.

Area of Science:

  • Obstetrics
  • Hematology
  • Transfusion Medicine

Background:

  • Blood transfusion is a common obstetric practice with inherent risks, including non-hemolytic and hemolytic reactions.
  • Donated blood is processed into components like packed red blood cells (PRBCs), platelets, and fresh frozen plasma (FFP).
  • Alternatives such as autotransfusion and blood substitutes exist, but transfusion remains prevalent.

Purpose of the Study:

  • To outline the physiological basis of blood transfusion.
  • To discuss the risks and alternatives to blood transfusion in obstetrics.
  • To provide guidelines for the safe and judicious use of blood products in obstetric patients.

Main Methods:

  • Review of physiological principles of blood transfusion.
  • Discussion of various blood components and their processing.

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  • Exploration of alternatives to allogeneic blood transfusion.
  • Analysis of clinical and hematological parameters for transfusion decisions.

    • Main Results:

    • Transfusion reactions occur with varying incidence, from 4% for non-hemolytic to 1 in 40,000 for hemolytic reactions.
    • Obstetricians may be overly aggressive in transfusing blood products.
    • Acute obstetric blood loss often stems from placenta previa, postpartum hemorrhage, or surgical complications.
    • Multidisciplinary involvement (obstetrician, anesthetist, hematologist, blood bank) is crucial.

    Conclusions:

    • Judicious use of blood transfusion in obstetrics is essential due to associated risks.
    • Decision-making for red cell transfusion lacks established criteria, relying on clinical and hematological assessment.
    • Early consultation and adherence to practical guidelines can optimize blood product utilization and patient safety.