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Updated: Jul 21, 2026

Establishment of a Clinic-based Biorepository
Published on: May 29, 2017
[Cutaneous squamous cell carcinoma: a review with consideration of special patient groups]
1Klinik für Dermatologie, Universitätsklinikum Essen, Westdeutsches Tumorzentrum, Universität Duisburg-Essen, Hufelandstr. 55, 45147, Essen, Deutschland, uwe.hillen@uk-essen.de.
Abstract:
The incidence of non-melanoma skin cancer (NMSC) is increasing. Squamous cell carcinoma of the skin (SCC) is a tumor of the elderly. Due to the increasing life expectancy, SCC will become more and more frequent in the future. Generally SCC has a favorable prognosis. Standard therapy is microscopically- controlled excision. Therapy of advanced and metastatic SCC is still challenging. Patients with regional lymph node metastasis have ten-year survival rates less than 20%; patients with distant metastases less than 10%. Immunosuppression has been shown to be one of the key prognostic factors for metastasis. The article reviews SCC and focusses on patients being at risk for an unfavorable course.
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