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An economical and safe procedure to synthesize 2-hydroxy-4-pentynoic acid: A precursor towards 'clickable'

Quanxuan Zhang1, Hong Ren2, Gregory L Baker1

  • 1Department of Chemistry, Michigan State University, East Lansing, Michigan 48824, USA.

Beilstein Journal of Organic Chemistry
|July 4, 2014
PubMed

Keywords:
2-hydroxy-4-pentynoic acidalkylationdecompositiondiethyl 2-acetamidomalonateone-potoptimizationpropargyl bromidepropargyl tosylatesafe and economical‘clickable’ polylactide‘click’ chemistry

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