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The Arch of Aorta01:10

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Aneurysm I: Introduction01:30

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Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
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Vasogenic edema is a major form of cerebral edema characterized by abnormal accumulation of fluid in the brain’s extracellular space due to disruption of the blood–brain barrier (BBB). The BBB is a specialized structure composed of endothelial cells connected by tight junctions, supported by astrocytic endfeet and a basement membrane. Under normal conditions, it tightly regulates the movement of ions, proteins, and solutes between the bloodstream and brain parenchyma. When this...
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Updated: Apr 27, 2026

Microsurgical Clip Obliteration of Middle Cerebral Aneurysm Using Intraoperative Flow Assessment
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Microsurgical Clip Obliteration of Middle Cerebral Aneurysm Using Intraoperative Flow Assessment

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Vertebrobasilar fusiform aneurysms.

Joseph C Serrone1, Yair M Gozal1, Aaron W Grossman1

  • 1Department of Neurosurgery, UC College of Medicine, Cincinnati, OH, USA.

Neurosurgery Clinics of North America
|July 5, 2014
PubMed
Summary
This summary is machine-generated.

Fusiform aneurysms, unlike berry aneurysms, often cause ischemic stroke. Traditional treatments focus on blood flow reduction, but new medical therapies may offer future options for patients unsuitable for surgery.

Keywords:
AneurysmDolichoectaticFusiformVertebralVertebrobasilar

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Area of Science:

  • Neurology
  • Vascular Surgery
  • Medical Innovation

Background:

  • Fusiform aneurysms differ from saccular/berry aneurysms in presentation, often leading to ischemic stroke or mass effect rather than subarachnoid hemorrhage.
  • Traditional management for fusiform vertebrobasilar aneurysms involves techniques aimed at reducing or reversing blood flow.
  • Recent attempts at flow diversion in the posterior circulation have yielded variable outcomes.

Purpose of the Study:

  • To explore the potential of modern medical therapies for treating fusiform aneurysms.
  • To consider alternative treatment strategies for fusiform aneurysms, particularly in patients with poor surgical candidacy.

Main Methods:

  • Review of existing literature on fusiform aneurysm pathophysiology and treatment.
  • Analysis of recent advancements in medical therapies relevant to vascular lesions.
  • Consideration of pathophysiologic processes that may be modulated by contemporary medical interventions.

Main Results:

  • Flow diversion in the posterior circulation has shown mixed results.
  • Understanding the pathophysiology of fusiform aneurysms suggests potential targets for medical intervention.
  • Medical management may become a viable option for specific patient groups.

Conclusions:

  • Future research may focus on medical treatments for fusiform aneurysms.
  • Medical therapy could be particularly beneficial for patients who are poor surgical candidates.
  • Evolving medical therapies offer new perspectives for managing complex vascular lesions like fusiform aneurysms.