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Published on: June 2, 2022
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Microbial endocrinology and the microbiota-gut-brain axis
1Department of Immunotherapeutics and Biotechnology, Texas Tech University Health Sciences Center, 1718 Pine Street, Abilene, TX, 79601, USA, mark.lyte@ttuhsc.edu.
Advances in Experimental Medicine and Biology
|July 6, 2014
Summary
Microbial endocrinology studies how microbes produce and recognize neurochemicals, bridging microbiology and neurobiology. This field explores the microbiota
Area of Science:
- Microbial endocrinology
- Neurobiology
- Microbiology
Background:
- Microbial endocrinology investigates the production and recognition of neurochemicals by microorganisms.
- It lies at the intersection of microbiology and neurobiology.
- Eukaryotic neurochemical signaling may have originated from horizontal gene transfer from prokaryotes.
Purpose of the Study:
- To explore the role of microbial endocrinology in understanding host behavior.
- To investigate the influence of the microbiota on host behavior.
- To examine how host neuroendocrine mechanisms affect the microbiota.
Main Methods:
- Theoretical framework integrating microbiology and neurobiology.
- Experimental design for studying microbiota-host interactions.
- Analysis of shared neuroendocrine signaling pathways.
Main Results:
- Microbial endocrinology provides a basis for testable experiments.
- Shared signaling mechanisms facilitate microbiota-host communication.
- The study highlights bidirectional communication between host and microbiota.
Conclusions:
- Microbial endocrinology is key to understanding microbiota's influence on host behavior.
- Neuroendocrine signaling is a crucial link between host and microbiota.
- This field offers insights into host-microbe interactions and potential therapeutic targets.
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