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¹⁸F-fluoride PET/computed tomography imaging.

Einat Even-Sapir1

  • 1Department of Nuclear Medicine, Tel-Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel-Aviv University, 6 Weizman Street, Tel-Aviv 64239, Israel.

PET Clinics
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PubMed
Summary

18F-fluoride PET/CT imaging is a sensitive tool for assessing bone abnormalities in both cancer and benign conditions. Its increasing availability makes it valuable for evaluating skeletal lesions and bone pathophysiology in clinical practice.

Keywords:
(18)F-fluorideBone imagingComputed tomographyPET/CT

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Area of Science:

  • Nuclear Medicine
  • Radiology
  • Oncology

Background:

  • The proliferation of cyclotrons and PET/CT scanners enhances the accessibility of 18F-fluoride PET/CT.
  • 18F-fluoride PET/CT is a well-established imaging modality for bone assessment.

Purpose of the Study:

  • To advocate for the broader clinical consideration of 18F-fluoride PET/CT.
  • To highlight its utility in evaluating bone abnormalities across various clinical scenarios.

Main Methods:

  • Review of accumulated data on 18F-fluoride PET/CT imaging.
  • Analysis of its sensitivity and scope in detecting skeletal lesions.

Main Results:

  • 18F-fluoride PET/CT demonstrates high sensitivity for detecting skeletal lesions.
  • The modality effectively assesses pathophysiologic processes in both normal and abnormal bone.

Conclusions:

  • 18F-fluoride PET/CT imaging should be integrated into routine clinical practice.
  • Its application extends beyond oncology to encompass benign bone conditions.