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Updated: Apr 26, 2026

Cefoperazone-treated Mouse Model of Clinically-relevant Clostridium difficile Strain R20291
Published on: December 10, 2016
[Clostridium difficile ribotype 027 is a challenge]
Trine Nyboe Sommer1, Pernille Ravn, Ida Gjørup
1Anæstesiologisk Afdeling Z, Bispebjerg Hospital, Bispebjerg bakke 23, 2400 København NV. trinenyboe@gmail.com.
Abstract:
Infection with Clostridium difficile is the primary infective cause of antibiotic-associated diarrhoea. In 2008, a major outbreak of CD027 took place in North Zealand, Denmark. We described this infection in a single medical department. Patients positive for C. difficile enlisted at Medical Department O, Herlev Hospital, in 2009 were included and demographic data were recorded. In total, 69 patients were included, average age 83 years, Charlson Comorbidity Score 4. Of all patients 24 died. Further studies are needed in order to treat and minimize infection with C. difficile.
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